ABO incompatibility and relapse risk in patients undergoing allogeneic marrow transplantation for acute myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Allogeneic marrow transplantation for acute nonlymphoblastic leukemia after first relapse.
Sixty-two patients with acute nonlymphoblastic leukemia in first relapse or second remission were treated with allogeneic marrow transplantation from HLA-matched siblings. In 17 patients (group 1), no attempt at reinduction of remission was made prior to transplantation. In 20 patients (group 2), attempts at inducing a second remission prior to transplantation were unsuccessful; and in 25 patie...
متن کاملOutcome for Patients Who Relapse After Allogeneic Bone Marrow Transplantation for Chronic Myeloid Leukemia
We studied the clinical course of 130 chronic myeloid leukemia (CML) patients (89 males and 41 females) in the European Bone Marrow Transplantation Group (EBMT) registry who received transplants before January 1, 1988 and who subsequently had evidence of recurrent leukemia. All patients had received a pretransplant conditioning regimen including total body irradiation (TBI). The first evidence ...
متن کاملRisk factors for relapse after allogeneic transplantation in acute myeloid leukemia.
Acute myeloid leukemia is a clonal neoplasm derived from myeloid progenitor cells with a varying outcome. The initial goal of treatment is the achievement of complete remission, defined for over 40 years by morphology. However, without additional post-remission treatment the majority of patients relapse. In many cases of acute myeloid leukemia, allogeneic stem cell transplantation offers the be...
متن کاملDonor leukocyte infusions for chronic myeloid leukemia in relapse after allogeneic bone marrow transplantation.
PURPOSE Treatment options for patients with chronic myeloid leukemia (CML) who relapse after allogeneic bone marrow transplantation (BMT) are limited. Treatment with lymphocytes from the original marrow donor and the influence on the malignant clone was studied in these patients. PATIENTS AND METHODS Seven patients with CML that had relapsed after BMT with T-cell-depleted grafts were treated....
متن کاملDonor Leukocyte Infusions for Chronic Myeloid Leukemia in Relapse after Allogeneic Bone Marrow Transplantation
Allogeneic bone marrow transplantation (BMT) is the only curative therapy for chronic myeloid leukemia (CML), but relapse occurs in approximately 10% of patients transplanted in chronic phase with non T-cell-depleted marrow.’” The risk of relapse is substantially greater if T-cell depletion of donor marrow is used as prophylaxis against graft-versus-host disease (GVHD), when relapse rates of 50...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2002
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1703706